منابع مشابه
Thrombotic cocktail in stroke.
A 35-year-old woman was admitted after a sudden left-arm deficit, which was preceded by 3 weeks of the same transient episodes lasting less than 5 minutes each. She was being treated for menorrhagia with tranexamic acid and was also using oral contraceptives. Three weeks before, she had a Mycoplasma pneumoniae respiratory infection. MRI showed a recent ischemia in the territories of the right m...
متن کاملSilent stroke in patients with acute thrombotic stroke
Introduction: Brain stroke is the most common neurologic disorder and also the most common cause of mortality and morbidity in neurtologic patients. Thanks to new methods of radiography such as MRI, brain vascular lesions including silent stroke are demonstrated more carefully. This study considers the frequency of silent stroke in patients with acute thrombotic stroke in Rafsanjan by using M...
متن کاملArgatroban in thrombotic stroke.
Evidence for the potential use of direct thrombin inhibition in the treatment of acute stroke is reviewed. Reduction of secondary microthrombi and improved regional collateral cerebral blood flow is the proposed mechanism of action of thrombin inhibition for the treatment of cerebral ischemia. A clinical study in Japan found that argatroban administered within 48 h of stroke symptom onset is sa...
متن کاملExperimental acute thrombotic stroke in baboons.
To study the effects of antithrombotic therapy in experimental stroke, we have characterized a baboon model of acute cerebrovascular thrombosis. In this model an inflatable silastic balloon cuff has been implanted by transorbital approach around the right middle cerebral artery (MCA), proximal to the take-off of the lenticulostriate arteries (LSA). Inflation of the balloon for 3 hours in six an...
متن کاملSynergy of Combined tPA-Edaravone Therapy in Experimental Thrombotic Stroke
Edaravone, a potent antioxidant, may improve thrombolytic therapy because it benefits ischemic stroke patients on its own and mitigates adverse effects of tissue plasminogen activator (tPA) in preclinical models. However, whether the combined tPA-edaravone therapy is more effective in reducing infarct size than singular treatment is uncertain. Here we investigated this issue using a transient h...
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ژورنال
عنوان ژورنال: Neurology
سال: 2005
ISSN: 0028-3878,1526-632X
DOI: 10.1212/01.wnl.0000142981.77895.c3